Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000).
Cadmium induces DNA synthesis and proliferation in macrophages;CTCF: First Multivalent Nuclear Factor;Erk1/Erk2 Mapk Signaling pathway;IL-2 Receptor Beta Chain in T cell Activation;Inhibition of Cellular Proliferation by Gleevec;MAPKinase Signaling Pathway;Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha);Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells;Overview of telomerase protein component gene hTert Transcriptional Regulation ;p38 MAPK Signaling Pathway ;Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy;Telomeres, Telomerase, Cellular Aging, and Immortality;Tumor Suppressor Arf Inhibits Ribosomal Biogenesis;WNT Signaling Pathway