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Risk Allele ? | Mapped Gene ? | 95% CI ? | Reported Trait ? | Study ? | Publication ? | |||
|---|---|---|---|---|---|---|---|---|
rs7412-? | APOE | 0.100 | 12.300 | 2.00e-9*** | [8.4-16.3] mg/dL decrease | LDL cholesterol | LJ | |
rs7412-T | APOE | 0.078 | 0.383 | 4.00e-10*** | [0.26-0.5] unit decrease | Pulse pressure | HR | |
rs7412-T | APOE | 0.079 | 0.084 | 3.00e-38*** | [0.071-0.097] (percentage) decrease | High light scatter reticulocyte percentage of red cells | WJ | |
rs7412-T | APOE | 0.079 | 0.081 | 1.00e-35*** | [0.068-0.094] unit decrease | High light scatter reticulocyte count | WJ | |
rs7412-T | APOE | 0.079 | 0.060 | 4.00e-20*** | [0.047-0.073] unit decrease | Reticulocyte fraction of red cells | WJ | |
rs7412-T | APOE | 0.078 | 0.156 | 6.00e-14*** | [0.12-0.2] mg/dl increase | HDL cholesterol | R | |
rs7412-T | APOE | 0.078 | 0.420 | 5.00e-94*** | [0.38-0.46] mg/dl decrease | Cholesterol, total | R | |
rs7412-T | APOE | 0.079 | 0.056 | 9.00e-18*** | [0.043-0.069] unit decrease | Reticulocyte count | WJ | |
rs7412-T | APOE | 0.066 | 0.374 | 8.00e-315*** | [0.36-0.39] unit decrease (EA Beta values) | Total cholesterol levels | CN | |
rs7412-T | APOE | 0.079 | 0.083 | 4.00e-38*** | [0.071-0.096] unit decrease | Immature fraction of reticulocytes | WJ | |
rs7412-C | APOE | 0.930 | 0.413 | 8.00e-239*** | [0.39-0.44] s.d. increase | Cholesterol, total | I | |
rs7412-C | APOE | 0.916 | 0.079 | 5.00e-29*** | unit decrease | High density lipoprotein cholesterol levels | TJ | |
rs7412-C | APOE | 0.952 | 0.152 | 2.00e-7 | unit decrease | High density lipoprotein cholesterol levels | TJ | |
rs7412-C | APOE | NR | 0.085 | 2.00e-36*** | unit decrease | High density lipoprotein cholesterol levels | TJ | |
rs7412-T | APOE | 0.061 | 0.040 | 2.00e-27*** | [-1.5672-1.6472] unit decrease | Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease | A | |
rs7412-T | APOE | 0.061 | 17.110 | 8.00e-78*** | [15.31-18.91] (nmol/min/ml) decrease | Lipoprotein phospholipase A2 activity in cardiovascular disease | A | |
rs7412-C | APOE | 0.916 | 0.493 | 1.00e-300*** | unit increase | Low density lipoprotein cholesterol levels | TJ | |
rs7412-C | APOE | 0.952 | 0.574 | 9.00e-59*** | unit increase | Low density lipoprotein cholesterol levels | TJ | |
rs7412-C | APOE | 0.892 | 0.522 | 2.00e-36*** | unit increase | Low density lipoprotein cholesterol levels | TJ | |
rs7412-C | APOE | NR | 0.498 | 1.00e-300*** | unit increase | Low density lipoprotein cholesterol levels | TJ | |
rs7412-T | APOE | NR | 2.780 | 3.00e-9*** | [1.69-3.87] unit decrease | Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms | S | |
rs7412-T | APOE | NR | 3.340 | 3.00e-10*** | [2.03-4.65] mg/dL decrease | Lipoprotein (a) levels | S | |
rs7412-C | APOE | 0.916 | 0.090 | 5.00e-31*** | unit decrease | Triglycerides | TJ | |
rs7412-C | APOE | NR | 0.087 | 2.00e-32*** | unit decrease | Triglycerides | TJ | |
rs7412-C | APOE | 0.892 | 0.381 | 3.00e-20*** | unit increase | Total cholesterol levels | TJ |
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